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CAS RN: 920-66-1 | Product Number: H1793
1,1,1,3,3,3-Hexafluoropropan-2-ol [for HPLC]
Purity: >99.5%(GC)
Chemical Substance Law (ENCS):
2-291
Synonyms:
- 1,1,1,3,3,3-Hexafluoro-2-propanol
- 1,1,1,3,3,3-Hexafluoroisopropyl Alcohol
- HFP
- HFIP
Documents:
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* For the case that without specific estimated shipping data, e.g.: If displayed as "will be shipped after 8 working days", the products will be shipped 8 working days later after ordering.
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Specifications
Appearance | Colorless to Almost colorless clear liquid |
Purity(GC) | min. 99.5 % |
Absorbance(210nm) | max. 0.800 |
Absorbance(220nm) | max. 0.400 |
Absorbance(230nm) | max. 0.200 |
Absorbance(254nm) | max. 0.080 |
Absorbance(400nm) | max. 0.030 |
Water | max. 0.5 % |
NMR | confirm to structure |
Properties (reference)
Melting Point | -4 °C |
Boiling Point | 58 °C |
Specific Gravity (20/20) | 1.62 |
Refractive Index | 1.28 |
Solubility in water | Soluble |
Solubility (soluble in) | Ether, Acetone |
GHS
Pictogram |
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Signal Word | Danger |
Hazard Statements | H302 + H332 : Harmful if swallowed or if inhaled. H314 : Causes severe skin burns and eye damage. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 : Wash contaminated clothing before reuse. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P405 : Store locked up. |
Related Laws:
Chemical Substance Law (ENCS) |
2-291 |
RTECS# | UB6450000 |
Transport Information:
UN Number | UN1760 |
Class | 8 |
Packing Group | III |
Application
1,1,1,3,3,3-Hexafluoropropan-2-ol: An Acidic Modifier in Buffers for Mobile Phases for Liquid Chromatography
1,1,1,3,3,3-Hexafluoropropan-2-ol (HFIP or HFP) has been used not only as a solvent but also as an acidic modifier in buffers for mobile phases for liquid chromatography (HPLC). This product has defined specifications suitable for HPLC measurements, such as absorbance data.
References
- Analysis of Oligonucleotides by HPLC-Electrospray Ionization Mass Spectrometry
- New procedure for the use of high-performance liquid chromatography-electrospray ionization mass spectrometry for the analysis of nucleotides and oligonucleotides
- A. Apffel, J. A. Chakel, S. Fischer, K. Lichtenwalter, W. S. Hancock, J. Chromatogr. A 1997, 777, 3.
- Ion-pair reversed-phase high-performance liquid chromatography analysis of oligonucleotides: Retention prediction
- The Role of Fluorinated Alcohols as Mobile Phase Modifiers for LC-MS Analysis of Oligonucleotides
Articles/Brochures
TCIMAIL
[Product Highlights] Buffer and Additives for LC Analysis of Oligonucleotides[TCIMAIL No.192] Guaranteed Analytical Reagents for Oligonucleotides
Documents (Note: Some products will not have analytical charts available.)
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