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CAS RN: 31282-04-9 | Product Number: H1509

Hygromycin B


Purity: >80.0%(HPLC)
Synonyms:
Documents:
200MG
€35.00
3   ≥20 
1G
€109.00
1   ≥20 

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Product Number H1509
Purity / Analysis Method >80.0%(HPLC)
Molecular Formula / Molecular Weight C__2__0H__3__7N__3O__1__3 = 527.52  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 31282-04-9
Reaxys Registry Number 66457
PubChem Substance ID 253661073
Merck Index (14) 4852
MDL Number

MFCD06795479

Specifications
Appearance White to Light yellow to Dark green powder to crystal
Purity(HPLC)(CAD) min. 80.0 area%
Specific rotation [a]20/D +18.0 to +23.0 deg(C=1, H2O)
Properties (reference)
Melting Point 180 °C(dec.)
Specific Rotation 20° (C=1,H2O)
Solubility in water Completely soluble
Solubility (very soluble in) Ethanol,Methanol
GHS
Pictogram Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled.
H318 : Causes serious eye damage.
H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P262 : Do not get in eyes, on skin, or on clothing.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
Related Laws:
EC Number 250-545-5
RTECS# WK2130000
Transport Information:
UN Number UN3462
Class 6.1
Packing Group I
HS Number 2940000080
Application
Hygromycin B: A Selective Reagent in Molecular Genetics Experiments on Cells

Hygromycin B is a water-soluble aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus. It is acts by binding to the 80S subunit of the bacterial ribosome and inhibiting protein synthesis. In molecular genetics, hygromycin B is used in genetic modification as a selective reagent to isolate prokaryotic and eukaryotic cells coupled to a gene coding for hygromycin resistance.

References


PubMed Literature


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