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CAS RN: 53179-09-2 | Product Number: I1049

Sisomicin Sulfate

Purity: >98.0%(HPLC)
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Product Number I1049
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__9H__3__7N__5O__7·2^^1/__2H__2SO__4 = 692.71  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 53179-09-2
Related CAS RN 32385-11-8
Reaxys Registry Number 5709343
PubChem Substance ID 354335157
Merck Index (14) 8550
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Specific rotation [a]20/D +98.0 to +104.0 deg(C=1, H2O)
Drying loss max. 5.0 %
Properties (reference)
Melting Point 73 °C
Boiling Point 155 °C
Specific Rotation 100° (C=1,H2O)
Pictogram Pictogram
Signal Word Danger
Hazard Statements H360 : May damage fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
EC Number 258-414-4
Transport Information:
HS Number 2941900000
Sisomicin Sulfate: An Aminoglycoside Antibiotic that is Effective against Pseudomonas aeruginosa

Sisomicin sulfate is a naturally occurring aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is bactericidal in action against a wide range of Gram-negative and Gram-positive bacteria, including Klebsiella species, Escherichia coli, Pseudomonas aeruginosa, Enterobacter species, and Proteus species. Sisomicin is closely related structurally to gentamicin [G0383], but in vitro studies have shown it to have superior activity to gentamicin against Pseudomonas aeruginosa. Sisomicin, like that of the other aminoglycoside antibiotics, binds the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of transcription. Consequently, bacterial protein synthesis is inhibited. (The product is for research purpose only.)


PubMed Literature

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