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CAS RN: 82956-11-4 | Product Number: N0959

Nafamostat Mesylate

Purity: >98.0%(HPLC)
  • 6-Amidino-2-naphthyl 4-Guanidinobenzoate Bis(methanesulfonate)
  • 4-Guanidinobenzoic Acid 6-Amidino-2-naphthyl Ester Bis(methanesulfonate)
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1   ≥20 

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Product Number N0959
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__9H__1__7N__5O__2·2CH__4O__3S = 539.58  
Physical State (20 deg.C) Solid
CAS RN 82956-11-4
Related CAS RN 81525-10-2
Reaxys Registry Number 5703937
PubChem Substance ID 253661919
Merck Index (14) 6350
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 95.0 %
Properties (reference)
Melting Point 258 °C
Solubility in water Soluble
Solubility (very slightly) Ethanol,Methanol
Solubility (insoluble in) Acetone,Ether
Related Laws: / Compliance with laws, Regulations
RTECS# DG2736000
Transport Information:
HS Number 2925290090

Nafamostat mesilate was first reported by Fujii and Hitomi in 1981 as a synthetic serine protease inhibitor. This compound inhibits various serine protease generated during the coagulation cascade and the inflammatory process. Nafamostat mesilate has been commonly used as an anticoagulant and reported as a drug for the treatments of DIC (disseminated intravascular coagulation) and acute pancreatitis and as an anticoagulant in extracorporeal circulation. (The product is for research purpose only.)


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