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CAS RN: 22189-32-8 | Product Number: S0584

Spectinomycin Dihydrochloride Pentahydrate


Purity: >98.0%(T)(N)
Synonyms:
Documents:
5G
€51.00
1   ≥20 
25G
€152.00
2   ≥20 

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Product Number S0584
Purity / Analysis Method >98.0%(T)(N)
Molecular Formula / Molecular Weight C__1__4H__2__4N__2O__7·2HCl·5H__2O = 495.35  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 22189-32-8
Related CAS RN 21736-83-4&1695-77-8
PubChem Substance ID 354335325
Merck Index (14) 8739
MDL Number

MFCD00150886

Specifications
Appearance White to Almost white powder to crystal
Purity(with Total Nitrogen) min. 98.0 %
Purity(Argentmetric Titration) min. 98.0 %
Specific rotation [a]20/D +15.0 to +21.0 deg(C=1,H2O)
Water 16.0 to 20.0 %
Properties (reference)
Melting Point 207 °C(dec.)
Specific Rotation 15° (C=1,H2O)
Solubility in water Completely soluble
Solubility (insoluble in) Ethanol
GHS
Related Laws:
RTECS# WG7400000
Transport Information:
HS Number 2941900000
Application
Spectinomycin Dihydrochloride: An Aminocyclitol Antibiotic Used for the Treatment of Infection with Streptomyces spectabilis and for Molecular Cloning

Spectinomycin dihydrochloride is an aminoglycoside antibiotic produced by a species of soil microorganism designated as Streptomyces spectabilis. Spectinomycin exerts its bactericidal activity by inhibiting protein synthesis in the bacterial cell; the site of action is the 30S ribosomal subunit. Spectinomycin is highly effective for the treatment of infections with Neisseria gonorrhoeae. In vitro studies have shown no cross-resistance of Neisseria gonorrhoeae between spectinomycin hydrochloride and benzylpenicillins [A2092] [P1770] [P1772]. On bioscience research, a resistance-conferring gene for spectinomycin can also be used as a selection marker in bacteria for molecular cloning purposes. In addition, spectinomycin is used as a selection agent for transformed plant cells that contain the selectable marker gene SpcR. (The product is for research purpose only.)

References


PubMed Literature


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