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CAS RN: 989-51-5 | Product Number: E0694
(-)-Epigallocatechin Gallate Hydrate
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Purity: >98.0%(HPLC)
Synonyms:
- EGCG Hydrate
- (-)-cis-3,4-Dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-1(2H)-benzopyran-3-yl Gallate Hydrate
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 100MG |
$99.00
|
4 | Contact Us | ≥100 |
|
| 500MG |
$273.00
|
4 | 1 | ≥100 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | E0694 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__1__8O__1__1·xH__2O = 458.38 (as Anhydrous) |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 500MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 989-51-5 |
| Related CAS RN | 1257-08-5 |
| Reaxys Registry Number | 67944 |
| PubChem Substance ID | 87558853 |
| Merck Index (14) | 3526 |
| MDL Number | MFCD00075940 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -165.0 to -186.0 deg(C=1, EtOH) |
| Water | max. 5.0 % |
Properties (reference)
| Melting Point | 212 °C |
| Specific Rotation | -176° (C=1,EtOH) |
| Solubility (soluble in) | Ethanol |
GHS
Related Laws:
| RTECS# | KB5200000 |
Transport Information:
| HS Number | 2934.99.4400 |
Application
Efflux pump research
(-)-Epigallocatechin Gallate has been reported to inhibit efflux pump thereby enhancing the activity of tetracycline [T3971, T2525] in Staphylococci.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Epigallocatechin-Gallate Enhances the Activity of Tetracycline in Staphylococci by Inhibiting Its Efflux from Bacterial Cells
- Epigallocatechin gallate inhibits the type III secretion system of Gram-negative enteropathogenic bacteria under model conditions
- Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells
- Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions (a review)
- Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications (a review)
- Green tea and its anti-angiogenesis effects (a review)
- Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review
- Molecular understanding of Epigallocatechin gallate (EGCG) in cardiovascular and metabolic diseases (a review)
Application
Type III secretion system (T3SS) research / Type III secretion system (T3SS) inhibitor
References
Application
(-)-Epigallocatechin Gallate (EGCG): A Polyphenolic Compound with Diverse Biological Activities including Anti-Cancer Effects
(-)-Epigallocatechin gallate (EGCG), a polyphenolic compound, is the ester of epigallocatechin [E1084] and gallic acid [G0011]. EGCG has been found in a variety of plants including green and black tea plants, and reported to have diverse biological activities including antioxidant, anti-cancer, anti-angiogenic and cardiovascular protective effects. (The product is for research purpose only.)
References
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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Analytical Charts
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