Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 145202-66-0 | Product Number: R0181
Rizatriptan Benzoate
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine Benzoate
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 50MG |
$148.00
|
1 | Contact Us | 8 |
|
| 250MG |
$484.00
|
1 | Contact Us | 22 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | R0181 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__9N__5·C__7H__6O__2 = 391.48 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 145202-66-0 |
| Reaxys Registry Number | 7066526 |
| PubChem Substance ID | 354334261 |
| Merck Index (14) | 8241 |
| MDL Number | MFCD00866224 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 %(total of Ion-Pair) |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 178.0 to 182.0 °C |
Properties (reference)
| Melting Point | 180 °C |
| Solubility in water | Soluble |
| Degree of solubility in water | 53 g/l |
| Solubility (soluble in) | Methanol |
| Solubility (slightly sol. in) | Ethanol |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
Transport Information:
| HS Number | 2933.99.5590 |
Application
Rizatriptan Benzoate: A Selective Serotonin 5-HT1B/1D Receptor Agonist
Rizatriptan benzoate is a derivative of tryptamine [T0890]. It is a selective serotonin 5-HT1B/1D receptor agonist used in the acute treatment of migraine. (The product is for research purpose only.)
References
- Synthesis and Serotonergic Activity of N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and Analogs: Potent Agonists for 5-HT1D Receptors
- The novel anti-migraine agent rizatriptan inhibits neurogenic dural vasodilation and extravasation
- Rizatriptan has central antinociceptive effects against durally evoked responses
- Mechanisms of Action of the 5-HT1B/1D Receptor Agonists (a review)
- A review of the 5-HT1B/1D agonist rizatriptan: update on recent research and implications for the future
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.