Product Document Searching Made Easy by 2D Code! | TCI Chemistry News June 2026 | [TCIPracticalExample] Oxidation Reaction of Heterocycles Using... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
请选择数量
CAS RN: 114-07-8 | 产品编码: E0751
Erythromycin
×
补充产品信息:
This product has not been tested for potency and is guaranteed for chemical purity.
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | -71.0 to -78.0 deg(C=2, EtOH)(calcd.on anh.substance) |
| Water | max. 10.0 % |
物性（参考值）
| 比旋光度 [α]D | -74° (C=2,EtOH) |
| 溶解性（可溶于） | 1,2-二氯乙烷, 乙醚 |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H317 : May cause an allergic skin reaction. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
| RTECS# | KF4375000 |
运输信息
| HS编码* | 2941.50-000 |
应用
Biofilm research
It has been reported that susceptibility of Actinobacillus actinomycetemcomitans, strain 310a, biofilm to erythromycin decreases as biofilm matures.1) Adding 10 mg/L of the antibiotic reduced biofilm development in the early phase, but it enhanced biofilm development in the mature phase.
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- Susceptibility of Actinobacillus actinomycetemcomitans to six antibiotics decreases as biofilm matures
- Erythromycin (a review)
- The macrolides: erythromycin, clarithromycin, and azithromycin (a review)
- Erythromycin resistance by ribosome modification (a review)
- Erythromycin and other macrolides as prokinetic agents (a review)
- Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases (a review)
应用
Erythromycin: The First Macrolide Antibiotic
Macrolide antibiotics are classified by the size of the macrocyclic lactone ring of aglycone as 14-, 15- or 16-membered ring macrolides. Macrolides are characterized by similar chemical structures, mechanisms of action and resistance, but vary in the different pharmacokinetic parameters, and spectrum of activity. Erythromycin (abbrev: EM), the first 14-membered macrolide, is isolated from a strain of the actinomycete Saccharopolyspora erythraea. EM has activity against a wide range of Gram-positive bacteria including Streptococcus and Staphylococcus, and limited activity against Gram-negative bacteria. EM inhibits protein synthesis in susceptible organisms by binding to specific nucleotides in 23S rRNA within the 50S subunit of the bacterial ribosome. EM and macrolides also shows gastrointestinal motor stimulating activity as a motilin-agonist, and anti-inflammatory or immunomodulatory activity. EM is easily inactivated by gastric acid. Therefore, a number of more stable macrolides such as azithromycin [A2076] and clarithromycin [C2220] have been chemically synthesized from EM.
References
PubMed Literature
文档
技术文章
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
请输入TCI产品编码
text.certificate.product.input.placeholder.kishida
中横线前的字母数字字符(4-5位)
text.certificate.lotno.input.placeholder.kishida
化学品安全说明书(SDS)
技术规格
没有搜索到技术规格。
如需更多帮助，请联 系我 们。
text.specification.search.errormsg.content.1.kishida
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
text.certificate.analysis.pdf.lotNumber.errorMessage.alphanumeric.kishida
• 请检查您输入的批号是否正确。批号是中横线前的4-5个字母数字字符。请仔细检查是O(字母)还是0(数字)，I(字母)还是1(数字)。
• 如果您输入的信息无误，请 联系我们 。
• text.certificate.analysis.pdf.errormsg.content6.kishida
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
text.certificate.analysis.pdf.lotNumber.errorMessage.alphanumeric.kishida
很抱歉，您搜索的分析图谱无法提供。