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CAS RN: 212322-56-0 | 产品编码: E1033
Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate
![Chemical Structure of Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate](/medias/E1033.jpg?context=bWFzdGVyfHJvb3R8NDEwNjR8aW1hZ2UvanBlZ3xhREJpTDJnMU5TODRPVEl4TmpFNE56RXdOVFU0TDBVeE1ETXpMbXB3Wnd8NmU1YTNkOWVlYmI2MjkyYjQwMGIxNjU4MmZiNmJmYjAxNDgxODZhYTRiMmVjOTc3NDQxMGQwNDZlYzczNjJlYg "Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate")
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![Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "Ethyl 3-[3-Amino-4-(methylamino)-N-(2-pyridyl)benzamido]propionate")
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 104.0 to 108.0 °C |
物性（参考值）
| 熔点 | 106 °C |
| 溶解性（可溶于） | 甲醇 |
GHS
相关法规
运输信息
| HS编码* | 2933.39-000 |
应用
A Synthetic Intermediate of Dabigatran and Its Derivatives
This product has been used as a synthetic intermediate of dabigatran [D5902, D5904 (Etexilate)] and its derivatives, which are direct thrombin inhibitors.
References
- Structure-based design of novel potent nonpeptide thrombin inhibitors
- Synthesis, characterization and suppression of impurities during optimization of Dabigatran etexilate
- Design, synthesis and structural exploration of novel fluorinated dabigatran derivatives as direct thrombin inhibitors
- Gradient RP-HPLC method for the determination of potential impurities in dabigatran etexilate in bulk drug and capsule formulations
参考文献
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技术规格
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