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CAS RN: 38304-91-5 | 产品编码: M1389
Minoxidil

产品编码 | M1389 |
纯度/分析方法 ![]() |
>98.0%(T)(HPLC) |
分子式/分子量 | C__9H__1__5N__5O = 209.25 |
外观与形状(20°C) | 固体 |
储存温度 ![]() |
室温 (15°C以下阴凉干燥处) |
储存在惰性气体下 | 存放于惰性气体之中 |
应避免的情况 | 空气 |
包装和容器 ![]() |
1G-Glass Bottle with Plastic Insert (查看图片) |
CAS RN | 38304-91-5 |
Reaxys-RN | 886240 |
PubChem物质ID | 87573342 |
Merck Index (14) | 6203 |
MDL编号 | MFCD00063409 |
技术规格
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Solubility in Acetic acid | almost transparency |
物性(参考值)
熔点 | 274 °C |
GHS
象形图 |
![]() |
信号词 | Warning |
危险性说明 | H302 : Harmful if swallowed. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
RTECS# | UV8200000 |
运输信息
HS编码* | 2933.59-000 |
应用
Minoxidil: An Opener of Vascular Smooth Muscle ATP Dependent K+ Channels
Minoxidil is an antihypertensive vasodilator agent and hair growth promoter that is metabolized by sulfation to the active compound, minoxidil sulfate [CAS: 83701-22-8]. The mode of action of the effects are still not completely understood, but the most plausible explanation is that minoxidil sulfate acts as an opener of vascular smooth muscle ATP dependent K+ (KATP) channels. Additionally, transdermal minoxidil delivery systems have been developed to increase the skin permeability.
References
- Enzymic and nonenzymic sulfation mechanisms in the biological actions of minoxidil (a review)
- Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells
- Minoxidil sulfate is the active metabolite that stimulates hair follicles (a review)
- Transdermal delivery of minoxidil with block copolymer nanoparticles
- Formulation and in vitro assessment of minoxidil niosomes for enhanced skin delivery
- Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil
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