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CAS RN: 10605-02-4 | 产品编码: P2138
Palmatine Chloride
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纯度/分析方法: >97.0%(HPLC)
别名：
- 氯化巴马汀
- 2,3,9,10-四甲氧基-5,6-二氢异喹啉并[3,2-a]异喹啉-7-鎓氯化物
- 7,8,13,13a-四脱氢-2,3,9,10-四甲氧基氯化小檗碱
- 5,6-二氢-2,3,9,10-四甲氧基二苯并[a,g]氯化喹啉
- 氯化黄藤素
- 2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium Chloride
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产品文档：
| 产品编码 | P2138 |
纯度/分析方法 
|
>97.0%(HPLC) |
| 分子式/分子量 | C__2__1H__2__2ClNO__4 = 387.86 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 10605-02-4 |
| Reaxys-RN | 3833339 |
| PubChem物质ID | 468592579 |
| MDL编号 | MFCD00016656 |
技术规格
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Water | max. 5.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 205 °C |
| 最大吸收波长 | 422 nm (H__2O) |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
| HS编码* | 2939.79-000 |
应用
Palmatine Chloride: An Alkaloid with a Wide Spectrum of Pharmacological Effects
Palmatine chloride, a close structural analog of berberine [B0450] [B0451], is found in Berberis vulgaris and Coptidis rhizoma which are widely used as traditional Chinese medicines (TCMs).1-3) Palmatine chloride and its analogues have been reported to exert a wide spectrum of pharmacological effects, including anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, anti-bacterial, anti-viral and regulating blood lipids.4,5) (The product is for research purpose only.)
References
- 1) Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine (a review)
- 2) Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity (a review)
- 3) A series of strategies for solving the shortage of reference standards for multi-components determination of traditional Chinese medicine, Mahoniae Caulis as a case
- 4) Synthesis and cytotoxicity evaluation of 13-n-alkyl berberine and palmatine analogues as anticancer agents
- 5) Palmatine: A review of its pharmacology, toxicity and pharmacokinetics (a review)
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