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CAS RN: 15500-66-0 | 产品编码: P2677
Pancuronium Bromide

纯度/分析方法: >95.0%(T)(HPLC)
别名:
- 泮库溴铵
- 二溴化潘可罗宁
- 1,1'-[(2β,3α,5α,16β,17β)-3,17-双(乙酰氧基)雄烷-2,16-二基]双(1-甲基哌啶鎓)二溴化物
- Pancuronium Dibromide
- 1,1'-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) Dibromide
产品文档:
产品编码 | P2677 |
纯度/分析方法 ![]() |
>95.0%(T)(HPLC) |
分子式/分子量 | C__3__5H__6__0Br__2N__2O__4 = 732.68 |
外观与形状(20°C) | 固体 |
储存温度 ![]() |
室温 (15°C以下阴凉干燥处) |
储存在惰性气体下 | 存放于惰性气体之中 |
应避免的情况 | 光,空气 |
包装和容器 ![]() |
200MG-Glass Bottle with Plastic Insert (查看图片) |
CAS RN | 15500-66-0 |
Reaxys-RN | 4226892 |
MDL编号 | MFCD00079223 |
技术规格
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 95.0 area% |
Purity(Nonaqueous Titration) | min. 95.0 % |
Specific rotation | +39.0 to +43.0 deg(C=3, water)(calcd.on anh.substance) |
Water | max. 5.0 % |
NMR | confirm to structure |
物性(参考值)
熔点 | 215 °C |
溶解性(可溶于) | 醇 |
GHS
象形图 |
![]() |
信号词 | Danger |
危险性说明 | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
RTECS# | TN4930000 |
运输信息
UN编号 | UN2811 |
类别 | 6.1 |
包装类别 | III |
HS编码* | 2933.39-000 |
应用
Pancuronium Bromide: A Nondepolarizing Neuromuscular Blocking Agent
Pancuronium bromide is a bis-quaternary amino-steroid compound possessing potent neuro-muscular blocking activity. There are reports that the mechanism of action is by competitively antagonizing the binding of acetylcholine to cholinergic receptors at the motor endplate. Therefore, it is used as a muscle relaxant. (The product is for research purpose only.)
References
- Pharmacology of pancuronium bromide, a new potent steroidal neuromuscular blocking agent
- Pancuronium Bromide: A Review of its Pharmacological Properties and Clinical Application
- Validation of a high-performance liquid chromatography method for the determination of pancuronium in Pavulon injections
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