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CAS RN: 130525-58-5 | 產品號碼: A3442
Zanamivir Azide Triacetate Methyl Ester
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| 產品號碼 | A3442 |
純度/分析方法 
|
>95.0%(HPLC) |
| 分子式 / 分子量 | C__1__8H__2__4N__4O__1__0 = 456.41 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| 包裝和容器
|
50MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 130525-58-5 |
| Reaxys-RN | 4359783 |
| PubChem Substance ID | 468590302 |
| MDL編號 | MFCD08704809 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 90.0 to 94.0 °C |
| Specific rotation | +102 to +108 deg(C=1, CHCl3) |
| NMR | confirm to structure |
性質
| 熔點 | 91 °C |
GHS
相關法規
運輸資料
| HS編碼* | 2932.99-000 |
Application
A Key Synthetic Intermediate of Zanamivir and its Analogs
This product has been used as a key synthetic intermediate of zanamivir [Z0023] which is an influenza virus neuraminidase inhibitor, and its analogs.
References
- The synthesis of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor
- Synthesis of the potent influenza neuraminidase inhibitor 4-guanidino Neu5Ac2en. X-ray molecular structure of 5-acetamido-4-amino-2,6-anhydro-3,4,5-trideoxy-D-erythro-L-gluco-nonionic acid
- Syntheses of triazole-modified zanamivir analogs via click chemistry and anti-AIV activities
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