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CAS RN: 3768-18-1 | 產品號碼: A3535
N4-Acetylcytidine
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| 產品號碼 | A3535 |
純度/分析方法 
|
>95.0%(T)(HPLC) |
| 分子式 / 分子量 | C__1__1H__1__5N__3O__6 = 285.26 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
| CAS RN | 3768-18-1 |
| Reaxys-RN | 624343 |
| MDL編號 | MFCD00006540 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Specific rotation | +55.0 to +59.0 deg(C=1, water) |
| NMR | confirm to structure |
性質
| 熔點 | 209 °C |
GHS
相關法規
運輸資料
| HS編碼* | 2934.99-000 |
Application
N4-Acetylcytidine: A Highly Conserved Modified RNA nucleoside
N4-Acetylcytidine (ac4C) is a highly conserved modified RNA nucleoside whose formation is catalyzed by the N-acetyltransferase 10 (NAT10). Recent studies have discovered that N4-acetylcytidine is a prevalent mRNA modification in eukaryotes and has roles in cell viability and development through these effects on RNA as follows; translation efficiency, mRNA stability, codon recognition, and tRNA structure, thereby opening up an emerging research field known as epitranscriptomics.
References
- Acetylation of Cytidine in mRNA Promotes Translation Efficiency
- The Processing, Gene Regulation, Biological Functions, and Clinical Relevance of N4-Acetylcytidine on RNA: A Systematic Review
- The emerging role of RNA modifications in the regulation of mRNA stability (a review)
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