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CAS RN: 64485-93-4 | 產品號碼: C2224
Cefotaxime Sodium Salt
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補充產品訊息:
This product has not been tested for potency and is guaranteed for chemical purity.
| 產品號碼 | C2224 |
純度/分析方法 
|
>96.0%(HPLC) |
| 分子式 / 分子量 | C__1__6H__1__6N__5NaO__7S__2 = 477.44 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Light Sensitive,Hygroscopic,Heat Sensitive |
| CAS RN | 64485-93-4 |
| 相關CAS RN
|
63527-52-6 |
| Reaxys-RN | 6564218 |
| PubChem Substance ID | 87560124 |
| SDBS (AIST Spectral DB) | 52166 |
| Merck Index(14) | 1933 |
| MDL編號 | MFCD00079073 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Purity(Nonaqueous Titration) | min. 96.0 % |
| Specific rotation [a]20/D | +58.0 to +64.0 deg(C=1, H2O)(calcd.on dried substance) |
| Drying loss | max. 3.0 % |
性質
| 熔點 | 163 °C(dec.) |
| 比旋光 [α]D | 61° (C=1,H2O) |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相關法規
| RTECS # | XI0250000 |
運輸資料
| HS編碼* | 2941.90-000 |
Application
Cefotaxime Sodium Salt: a Third Generation Cephalosporin Antibiotic
Cefotaxime sodium salt is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminocephalosporanic acid (7-ACA) [A1266]. It has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria, and is generally more active against Gram-negative bacteria than the first and second generation cephalosporins. It has increased stability to β-lactamases compared with the first and second generation cephalosporins. Furthermore, it penetrates well into various body compartments. Recently, it has been reported it as a corrosion inhibitor for mild steel in hydrochloric acid solution.
References
- Cefotaxime: a review of in vitro antimicrobial properties and spectrum of activity
- Cefotaxime (an overview)
- Drug utilization review (DUR) of the third generation cephalosporins: Focus on ceftriaxone, ceftazidime and cefotaxime
- Cefotaxime and desacetylcefotaxime antimicrobial interactions. The clinical relevance of enhanced activity: a review
- Cefotaxime sodium: A new and efficient corrosion inhibitor for mild steel in hydrochloric acid solution
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