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CAS RN: 59870-68-7 | 產品號碼: G0534
Glabridin
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純度/分析方法: >98.0%(GC)
别名:
- (R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl)-1,3-benzenediol
- 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]-1,3-benzenediol
- (R)-4-(8,8-Dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl)benzene-1,3-diol
文件：
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| 產品號碼 | G0534 |
純度/分析方法 
|
>98.0%(GC) |
| 分子式 / 分子量 | C__2__0H__2__0O__4 = 324.38 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Frozen (<0°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器
|
1G-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 59870-68-7 |
| Reaxys-RN | 7141956 |
| MDL編號 | MFCD03427694 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 228.0 to 232.0 °C |
| Specific rotation | +8.5 to +10.5 deg(C=0.5, methanol) |
| NMR | confirm to structure |
性質
| 熔點 | 230 °C |
| 溶解性（可溶於） | Ethanol |
GHS
相關法規
| RTECS # | CZ8937649 |
運輸資料
| HS編碼* | 2932.99-000 |
Application
Paraptosis research / Paraptosis like cell death
Reference
- Glabridin induces paraptosis-like cell death via ER stress in breast cancer cells
- Phytochemistry and biological properties of glabridin (a review)
- Pharmacological properties of glabridin (a flavonoid extracted from licorice): A comprehensive review
- Review on the Diverse Biological Effects of Glabridin
- Simultaneous extraction and separation of liquiritin, glycyrrhizic acid, and glabridin from licorice root with analytical and preparative chromatography
- Rapid RP-HPLC Method for the Quantification of Glabridin in Crude Drug and in Polyherbal Formulation
Application
Glabridin: A Prenylated Isoflavonoid with Various Biological Properties
Glabridin is a prenylated isoflavonoid specifically found in the roots of licorice (Glycyrrhiza glabra L.), and has various biological properties such as antioxidant, anti-inflammatory, anti-tumor, anti-microorganism, anti-atherogenic, energy metabolism regulator, estrogenic, neuroprotective, anti-osteoporotic, skin whitening, and GABAergic inhibition. In addition, many signaling pathways, including NF-κB, MAPK, Wnt/β-catenin, ERα/SRC-1, PI3K/AKT, and AMPK, have been implicated in the regulatory activities of glabridin. (The product is for research purpose only.)
References
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