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CAS RN: 83919-23-7 | 產品號碼: M2354
Mometasone Furoate
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| 產品號碼 | M2354 |
純度/分析方法 
|
>98.0%(HPLC) |
| 分子式 / 分子量 | C__2__7H__3__0Cl__2O__6 = 521.43 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器
|
1G-Glass Bottle with Plastic Insert （閲覽圖片）, 200MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 83919-23-7 |
| Reaxys-RN | 4340538 |
| PubChem Substance ID | 172088987 |
| Merck Index(14) | 6241 |
| MDL編號 | MFCD00866003 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 212.0 to 216.0 °C |
| Specific rotation [a]20/D | +48.0 to +52.0 deg(C=0.5、MeOH) |
| NMR | confirm to structure |
性質
| 熔點 | 214 °C(dec.) |
| 比旋光 [α]D | 50° (C=0.5,MeOH) |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H361 : Suspected of damaging fertility or the unborn child. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相關法規
| RTECS # | TU3822000 |
運輸資料
| HS編碼* | 2937.22-000 |
Application
Studies on Biological Activity of Mometasone
References
- A review of the pharmacology and pharmacokinetics of inhaled fluticasone propionate and mometasone furoate
- In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids
- C. L. Smith, W. Kreutner, Arzneim.-Forsch. 1998, 48, 956.
- The inhibitory effects of topically active glucocorticoids on IL-4, IL-5, and interferon-gamma production by cultured primary CD4+ T cells
- Effects of monotherapy with intra-nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis
- Progesterone receptor ligand binding pocket flexibility: crystal structures of norethindrone and mometasone furoate complexes
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