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CAS RN: 20554-84-1 | 產品號碼: P1982
| 產品號碼 | P1982 |
純度/分析方法 
|
>97.0%(HPLC) |
| 分子式 / 分子量 | C__1__5H__2__0O__3 = 248.32 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 應避免的情況 | Heat Sensitive |
| 包裝和容器
|
100MG-Glass Bottle with Plastic Insert （閲覽圖片）, 25MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 20554-84-1 |
| Reaxys-RN | 17582 |
| PubChem Substance ID | 135727274 |
| Merck Index(14) | 7048 |
| MDL編號 | MFCD00134592 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Specific rotation [a]20/D | -81.0 to -86.0 deg(C=1, CHCl3) |
性質
| 熔點 | 115 °C |
| 比旋光 [α]D | -84° (C=1,CHCl3) |
| 溶解性（可溶於） | Chloroform |
GHS
相關法規
| RTECS # | LY4220000 |
運輸資料
| HS編碼* | 2932.99-000 |
Application
Type IV secretion system (T4SS) research
Reference
- Chemical Genetics Reveals Bacterial and Host Cell Functions Critical for Type IV Effector Translocation by Legionella pneumophila
Application
Parthenolide: A Sesquiterpene Lactone with Potent Anticancer and Anti-Inflammatory Activities
Parthenolide, a sesquiterpene lactone, is originally isolated from the shoots of feverfew (Tanacetum parthenium) which is a traditional medical plant used commonly to prevent migraine headaches. Parthenolide has been reported to show potent anticancer and anti-inflammatory activities. For example, parthenolide inhibits the transcription factor NF-κB, and induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. (The product is for research purpose only.)
References
- The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex
- The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
- The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
- Parthenolide, a Sesquiterpene Lactone, Expresses Multiple Anti-cancer and Anti-inflammatory Activities (a review)
- Parthenolide: from plant shoots to cancer roots (a review)
考研文獻
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