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CAS RN: 568-73-0 | 產品號碼: T4153
| 產品號碼 | T4153 |
純度/分析方法 
|
>95.0%(HPLC) |
| 分子式 / 分子量 | C__1__8H__1__2O__3 = 276.29 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Refrigerated (0-10°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Hygroscopic,Heat Sensitive |
| 包裝和容器
|
250MG-Glass Bottle with Plastic Insert （閲覽圖片） |
| CAS RN | 568-73-0 |
| Reaxys-RN | 237369 |
| MDL編號 | MFCD00210563 |
產品規格
| Appearance | Red to Dark red powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 230.0 to 234.0 °C |
| NMR | confirm to structure |
性質
| 熔點 | 231 °C |
GHS
| 危險性說明 | H413 : May cause long lasting harmful effects to aquatic life. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
相關法規
| RTECS # | SF8282630 |
運輸資料
| HS編碼* | 2932.99-000 |
Application
Tanshinone I: A Major Lipophilic Component Extracts from the Root of Salvia miltiorrhiza
Tanshinone I, a derivative of phenanthrenequinone, is a major lipophilic component extracted from the root of Salvia miltiorrhiza, which is widely used in Chinese herbal medicine for the treatment of cardiovascular diseases. Biological studies suggested that tanshinone I shows a variety of pharmacological activities, such as anticancer, anti-inflammatory, amyloid-β anti-aggregation and cardio-cerebrovascular protective activities. (The product is for research purpose only.)
Reference
- Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
- Anticancer effects of tanshinone I in human non-small cell lung cancer
- Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses
- S. Y. Kim, T. C. Moon, H. W. Chang, K. H. Son, S. S. Kang, H. P. Kim, Phytother. Res. 2002, 16, 616.
- Research and development of natural product Tanshinone I: pharmacology, total synthesis, and structure modifications (a review)
- Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells
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