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CAS RN: 56-12-2 | Product Number: A0282
4-Aminobutyric Acid
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Purity: >99.0%(T)
Synonyms:
- GABA
Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25G |
$32.00
|
4 | Contact Us | ≥40 |
|
| 100G |
$88.00
|
6 | 5 | 15 |
|
| 500G |
$184.00
|
2 | Contact Us | ≥40 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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Specifications
| Appearance | White powder to crystaline |
| Purity(Nonaqueous Titration) | min. 99.0 % |
| Solubility in Water | almost transparency |
Properties (reference)
| Melting Point | 195 °C(dec.) |
GHS
Related Laws:
| RTECS# | ES6300000 |
Transport Information:
| HS Number | 2922.49.4950 |
Application
GABA: A Major Inhibitory Neurotransmitter in Nervous System
4-Aminobutyric acid (γ-aminobutyric acid or GABA) is a major inhibitory neurotransmitter in nervous system, the first report by Hayashi et al. in 1950s. GABA is present not only in the central nervous system but also in the peripheral nervous system. GABA plays the principal role in modulating neuronal excitability throughout the nervous system. Moreover, GABA is involved in a variety of biological functions such as proliferation, differentiation, migration and growth of neurons. GABA functions appear to be triggered by binding of GABA to its ionotropic receptors (GABAA and GABAC) which are ligand-gated chloride channels, and its metabotropic receptors GABAB which are coupled to G-proteins.
References
- Inhibition and excitation due to gamma-aminobutyric acid in the central nervous system.
- Excitatory actions of GABA during development: the nature of the nurture (a review)
- GABA and GABA receptors in the central nervous system and other organs (a review)
- GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations (a review)
- Extracellular level of GABA and Glu: in vivo microdialysis-HPLC measurements
- Determination and Comparison of γ-Aminobutyric Acid (GABA) Content in Pu-erh and Other Types of Chinese Tea
PubMed Literature
Articles/Brochures
TCIMAIL
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