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CAS RN: 56-12-2 | Product Number: A0282

4-Aminobutyric Acid


Purity: >99.0%(T)
Synonyms:
  • GABA
Documents:
25G
$23.00
11   7   ≥20 
100G
$70.00
3   4   ≥20 
500G
$145.00
2   4   ≥20 

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Product Number A0282
Purity / Analysis Method >99.0%(T)
Molecular Formula / Molecular Weight C__4H__9NO__2 = 103.12  
Physical State (20 deg.C) Solid
CAS RN 56-12-2
Reaxys Registry Number 906818
PubChem Substance ID 87561936
SDBS (AIST Spectral DB) 1075
Merck Index (14) 430
MDL Number

MFCD00008226

Specifications
Appearance White powder to crystaline
Purity(Nonaqueous Titration) min. 99.0 %
Solubility in Water almost transparency
Properties (reference)
Melting Point 195 °C(dec.)
GHS
Related Laws: / Compliance with laws, Regulations
RTECS# ES6300000
Transport Information:
HS Number 2922.49.4950
Application
GABA: A Major Inhibitory Neurotransmitter in Nervous System

4-Aminobutyric acid (γ-aminobutyric acid or GABA) is a major inhibitory neurotransmitter in nervous system, the first report by Hayashi et al. in 1950s. GABA is present not only in the central nervous system but also in the peripheral nervous system. GABA plays the principal role in modulating neuronal excitability throughout the nervous system. Moreover, GABA is involved in a variety of biological functions such as proliferation, differentiation, migration and growth of neurons. GABA functions appear to be triggered by binding of GABA to its ionotropic receptors (GABAA and GABAC) which are ligand-gated chloride channels, and its metabotropic receptors GABAB which are coupled to G-proteins.

References


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