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CAS RN: 89-57-6 | Product Number: A0317

5-Aminosalicylic Acid


Purity: >98.0%(T)
Synonyms:
  • 5-Amino-2-hydroxybenzoic Acid
  • Mesalamine
  • Mesalazine
  • 5-ASA
Documents:
25G
$27.00
3   1   ≥40 
500G
$208.00
5   1   27  

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Product Number A0317
Purity / Analysis Method >98.0%(T)
Molecular Formula / Molecular Weight C__7H__7NO__3 = 153.14 
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Air Sensitive
CAS RN 89-57-6
Reaxys Registry Number 2090421
PubChem Substance ID 87561970
SDBS (AIST Spectral DB) 3423
Merck Index (14) 5904
MDL Number

MFCD00007877

Specifications
Appearance White to Gray to Brown powder to crystal
Purity(Neutralization titration) min. 98.0 %
Solubility in HCl almost transparency
Properties (reference)
Melting Point 265 °C(dec.)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
Related Laws:
RTECS# VO1400000
Transport Information:
HS Number 2922.50.4000
Application
5-Aminosalicylic Acid (5-ASA): A Gastrointestinal Anti-Inflammatory Agent

5-Aminosalicylic acid (5-ASA or mesalazine) is used as a gastrointestinal anti-inflammatory agent. Although the mechanism of action remains unknown exactly, 5-ASA has in vitro and in vivo pharmacologic effects that decrease leukotriene production, scavenge for free radicals and inhibit leukocyte chemotaxis et al. For clinical purposes, amylose, ethyl cellulose or pH-dependent polymers coated 5-ASA are developed and used for drug delivery to the intestinal tract. In addition, sulfasalazine [S0580] is a prodrug of 5-ASA. (The product is for research purpose only.)

References


PubMed Literature


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