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CAS RN: 129-56-6 | Product Number: A2548

Anthra[1,9-cd]pyrazol-6(2H)-one


Purity: >95.0%(HPLC)
Synonyms:
  • Dibenzo[cd,g]indazol-6(2H)-one
  • SP 600125
Product Documents:
25MG
$138.00
3   1   7  

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Product Number A2548
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__1__4H__8N__2O = 220.23 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Condition to Avoid Heat Sensitive
CAS RN 129-56-6
Reaxys Registry Number 746890
PubChem Substance ID 253659651
MDL Number

MFCD00022289

Specifications
Appearance Light yellow to Yellow to Green powder to crystal
Purity(HPLC) min. 95.0 area%
Properties (reference)
Melting Point 282 °C
GHS
Related Laws:
RTECS# CB4585000
Transport Information:
HS Number 2933.99.7900
Application
LRRK2 Inhibitory Effect of SP600125

This product (SP600125) is an inhibitor of Jun N-terminal kinase (JNK), which is a stress-activated protein kinase that can be induced by inflammatory cytokines, bacterial endotoxin, osmotic shock, UV radiation, and hypoxia. In addition, there is a report that SP600125 inhibits LRRK2 (Leucine-rich repeat kinase 2) -G2019S, which is a promising therapeutic target for the treatment of Parkinson's disease, in the low micro-molar range. (The product is for research purpose only.)

References


Application
Apoptosis

References


Application
c-Jun N-Terminal Kinase (JNK) Inhibitor

References


PubMed Literature


Product Documents (Note: Some products will not have analytical charts available.)
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