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CAS RN: 20874-52-6 | Product Number: A3405
Saikosaponin D
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Purity: >98.0%(HPLC)
Synonyms:
- 16α,23-Dihydroxy-13,28-epoxyolean-11-en-3β-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside
Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10MG |
$105.00
|
Contact Us | Contact Us | 7 |
|
| 50MG |
$316.00
|
Contact Us | Contact Us | ≥40 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | A3405 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__4__2H__6__8O__1__3 = 780.99 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 20874-52-6 |
| Reaxys Registry Number | 5721325 |
| PubChem Substance ID | 468590281 |
| MDL Number | MFCD09028095 |
Specifications
Properties (reference)
| Melting Point | 218 °C |
GHS
Related Laws:
| RTECS# | VN3099000 |
Transport Information:
| HS Number | 2938.90.0000 |
Application
Saikosaponin D: An Active Component of Radix Bupleuri
Saikosaponin A [A3408], C [A3189], and D are triterpenoid saponins, and are isolated form Radix Bupleuri which has been used as a traditional medicine for more than 2000 years in Asia countries. It has been reported that they exert diverse biological activities, including anti-inflammatory, antitumor, antiviral, anti-allergic, immunoregulation, and neuroregulation activities mainly through NF-κB, MAPK or other pathways. (The product is for research purpose only.)
References
- Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway
- Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells
- A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applications
- Evaluation of traditional Chinese herbal medicine: Chaihu (Bupleuri Radix) by both high-performance liquid chromatographic and high-performance thin-layer chromatographic fingerprint and chemometric analysis
Documents (Note: Some products will not have analytical charts available.)
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Specifications
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