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CAS RN: 141433-60-5 | Product Number: B0450

Berberine Chloride Hydrate


Purity: >98.0%(T)(HPLC)
Synonyms:
  • Natural Yellow 18 Hydrate
Documents:
5G
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25G
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Product Number B0450
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__0H__1__8ClNO__4·xH__2O = 371.82 (as Anhydrous)
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic
CAS RN 141433-60-5
Related CAS RN 2086-83-1&633-65-8
Reaxys Registry Number 3836585
PubChem Substance ID 87563487
Merck Index (14) 1154
Colour Index 75160
MDL Number

MFCD00011939

Specifications
Appearance White to Yellow to Orange powder to crystaline
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %(calcd.on anh.substance)
Solubility in hot Water almost transparency
Water 8.0 to 12.0 %
Properties (reference)
Melting Point 145 °C(dec.)
GHS
Related Laws:
RTECS# DR9866400
Transport Information:
HS Number 2939.80.0000
Application
Bone research

References


Application
Efflux pump inhibitor

Berberine can potentially inhibit a diverse range of different efflux pumps, including the resistance nodulation division (RND) family. 1,2)

References


Application
Berberine Chloride: An Isoquinoline Alkaloid with Multispectrum Activities

Berberine chloride, an isoquinoline alkaloid extracted from Goldenseal (Hydrastis canadensis L.) and many other plants, has been used in Traditional Chinese and Indian (Ayurvedic) medicines for its antimicrobial and antiprotozoal properties.1) Recent pharmacological studies on berberine have revealed its various pharmacological activities,1) such as anti-cancer,2) anti-inflammatory,3) anti-arrhythmic,4) anti-diabetic,5,6) cholesterol-lowering7) and neuroprotective effects,8) yet the exact mechanisms are unknown. However, it is reported that berberine is able to activate an enzyme called Adenosine Monophosphate-Activated Protein Kinase (AMPK).5,6) (The product is for research purpose only.)

References


PubMed Literature


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