Register today for easy order tracking, quick service, and free shipping on orders over $75!
Maximum quantity allowed is 999
CAS RN: 128-08-5 | Product Number: B0656
|Size||Unit Price||Philadelphia, PA||Portland, OR||Japan*||Quantity|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
|Purity / Analysis Method||>98.0%(T)|
|Molecular Formula / Molecular Weight||C__4H__4BrNO__2 = 177.99|
|Physical State (20 deg.C)||Solid|
|Store Under Inert Gas||Store under inert gas|
|Condition to Avoid||Light Sensitive,Moisture Sensitive,Heat Sensitive|
|Reaxys Registry Number||113916|
|PubChem Substance ID||87563662|
|SDBS (AIST Spectral DB)||1944|
|Merck Index (14)||1438|
|Appearance||White to Orange to Green powder to crystal|
|Purity(Iodometric Titration)||min. 98.0 %|
|Melting Point||176 °C(dec.)|
|Boiling Point||339 °C|
|Solubility in water||Slightly soluble|
|Degree of solubility in water||14.7 g/l 25 °C|
|Solubility (soluble in)||Acetone|
|Solubility (very slightly)||Ether|
|Hazard Statements||H302 : Harmful if swallowed.
H314 : Causes severe skin burns and eye damage.
H290 : May be corrosive to metals.
|Precautionary Statements||P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dusts or mists.
P270 : Do not eat, drink or smoke when using this product.
P234 : Keep only in original container.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P390 : Absorb spillage to prevent material damage.
P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 : Wash contaminated clothing before reuse.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
P406 : Store in corrosive resistant container with a resistant inner liner.
P405 : Store locked up.
|UN Number (DOT-AIR)||UN3261|
|Packing Group (TCI-A)||III|
A solution of 2-methylbenzo[b]thiophene (500 mg, 3.4 mmol) in acetonitrile (5 mL) was stirred under nitrogen at 0 ˚C. Then NBS (630 mg, 3.5 mmol) was added the solution. The ice bath was removed and the mixture was stirred at room temperature for 30 min. The reaction mixture was quenched with water and extracted with dichloromethane. The organic layer was dried over anhydrous sodium sulfate and filtered. The solvent was removed under reduced pressure and the crude was purified by silica gel column chromatography (hexane, Rf = 0.65) to give 3-bromo-2-methylbenzo[b]thiophene as a white solid (759 mg, 99% yield).
The reaction mixture was monitored by TLC (hexane, Rf = 0.65).
1H NMR (270 MHz, CDCl3); δ 7.70-7.75 (m, 2H), 7.30-7.44 (m, 2H), 2.56 (s, 3H).
- Reactive ligand influence on initiation in phenylene catalyst-transfer polymerization
To a vial, Piv-protected amine (1 eq.), AgNO3 (4 eq.), (NH4)2S2O8 (4 eq.), and NCS or NBS (4 eq.) is added and dissolved in 1:9 acetone:water (0.2 M). The resulting mixture is stirred at room temperature. After 30 minutes, the reaction mixture is partitioned between EtOAc and H2O and separated. The aqueous layer is extracted with EtOAc in triplicate and the combined organic layers concentrated in vacuo. The crude mixture is then purified over silica column eluting with an EtOAc:Hex. Mixture to afford the desired haloamine product.
- Deconstructive diversification of cyclic amines
[Research Articles] Carbon-Heteroatom Bond Formation at the Benzylic Position of Methylarenes
Safety Data Sheet (SDS)
The requested SDS is not available.
Please Contact Us for more information.
C of A & Other Certificates
The requested analytical chart is not available. Sorry for the inconvenience.