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CAS RN: 51333-22-3 | Product Number: B3909

Budesonide


Purity: >98.0%(HPLC)
Synonyms:
  • (+)-16α,17α-Butylidenedioxy-11β,21-dihydroxy-1,4-pregnadiene-3,20-dione
Documents:
200MG
$59.00
1   1   ≥40 
1G
$200.00
7   2   26  

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Product Number B3909
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__5H__3__4O__6 = 430.54 
Physical State (20 deg.C) Solid
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image),  200MG-Glass Bottle with Plastic Insert (View image)
CAS RN 51333-22-3
Reaxys Registry Number 3633996
PubChem Substance ID 160871371
Merck Index (14) 1468
MDL Number

MFCD00083259

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 % (total of isomers)
Elemental analysis(Carbon) 68.00 to 71.00 %
Specific rotation [a]20/D +100 to +110 deg(C=0.28、CH2Cl2)
Properties (reference)
Specific Rotation 105° (C=0.28,CH2Cl2)
Solubility in water Insoluble
Solubility (soluble in) Chloroform, Methanol
Solubility (slightly sol. in) Acetone, Ethanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
Related Laws:
RTECS# TU3723000
Transport Information:
HS Number 2937.29.9095
Application
Budesonide: A Potent Glucocorticoid Receptor Antagonist

Budesonide is an anti-inflammatory corticosteroid that exhibits potent glucocorticoid activity and weak mineralocorticoid activity.1-6) Budesonide has a strong affinity for glucocorticoid receptor, and it is reported that budesonide has approximately 8.5-fold, 15-fold, and 195-fold greater than those of dexamethasone [D1961], prednisolone [P0637], and hydrocortisone [H0533], respectively.6) Budesonide is mainly metabolized by CYP3A4.6) (The product is for research purpose only.)

References


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