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CAS RN: 714971-09-2 | Product Number: B5520


Purity: >98.0%(HPLC)
  • AC 480
  • (S)-Morpholin-3-ylmethyl [4-[[1-(3-Fluorobenzyl)-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate
1   1   7  
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Product Number B5520
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__7H__2__7FN__8O__3 = 530.56  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 714971-09-2
Reaxys Registry Number 18544666
MDL Number


Appearance White to Light yellow to Light orange powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 20.00 to 22.00 %
Properties (reference)
Related Laws:
Transport Information:
HS Number 2934.99.4400
BMS-599626: A Highly Selective Inhibitor of HER1 and HER2

BMS-599626 (or AC480) is a highly selective inhibitor of human epidermal growth factor receptors (HER) kinase family which plays essential roles in regulating cell proliferation, survival, differentiation and migration. BMS-599626 modulates signaling and growth of tumor cells that depend on HER1 and/or HER2. Reportedly, BMS-599626 inhibits HER1 and HER2 with IC50 of 20 and 30 nmol/L, respectively. (The product is for research purpose only.)


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