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CAS RN: 104376-79-6 | Product Number: C2226

Ceftriaxone Disodium Salt Hemiheptahydrate


Purity: >98.0%(T)(HPLC)
Synonyms:
Documents:
5G
$91.00
7   1   ≥40 
25G
$263.00
2   8   ≥40 

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Note:

This product has not been tested for potency and is guaranteed for chemical purity.

Product Number C2226
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__8H__1__6N__8Na__2O__7S__3·3^^1/__2H__2O = 661.58 
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 104376-79-6
Related CAS RN 73384-59-5&74578-69-1
Reaxys Registry Number 9110623
PubChem Substance ID 87560125
MDL Number

MFCD00941454

Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D -150 to -170 deg(C=1, H2O)(calcd.on anh.substance)
Water 8.0 to 11.0 %
Properties (reference)
Melting Point 236 °C
Specific Rotation -160° (C=1,H2O)
Solubility in water Soluble
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P285 : In case of inadequate ventilation wear respiratory protection.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P272 : Contaminated work clothing must not be allowed out of the workplace.
P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304 + P341 : IF INHALED: If breathing is difficult, remove person to fresh air and keep comfortable for breathing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
Related Laws:
RTECS# XI0368800
Transport Information:
HS Number 2941.90.5000
Application
Ceftriaxone Disodium: A Third Generation Semisynthetic Cephalosporin Antibiotic with Longer Serum Half-Life

Ceftriaxone disodium salt is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminocephalosporanic acid (7-ACA) [A1266]. It has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria, and is generally more active against Gram-negative bacteria than the first and second generation cephalosporins. It has increased stability to β-lactamases compared with the first and second generation cephalosporins. Incorporation of the triazine substituted side chain into the 3-position of the cephalosporin nucleus markedly prolong serum half-life.

References


PubMed Literature


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