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CAS RN: 69712-56-7 | Product Number: C2936

Cefotetan


Purity: >98.0%(HPLC)
Synonyms:
Documents:
250MG
$191.00
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Note:

This product has not been tested for potency and is guaranteed for chemical purity.

Product Number C2936
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__7H__1__7N__7O__8S__4 = 575.60 
Physical State (20 deg.C) Solid
Storage Temperature -20°C
Condition to Avoid Heat Sensitive
CAS RN 69712-56-7
Reaxys Registry Number 5697364
PubChem Substance ID 253662091
Merck Index (14) 1934
MDL Number

MFCD00864983

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 97.0 %
Specific rotation [a]20/D +115.0 to +122.0 deg(C=1,0.5%NaHCO3 sol.(0.5%))
Properties (reference)
Specific Rotation 118° (C=1,0.5% NaHCO3)
Solubility (slightly sol. in) Methanol
GHS
Related Laws:
RTECS# XI0330800
Transport Information:
HS Number 2941.90.3000
Application
Cefotetan: A (7S)-Methoxy Cephalosporin (Cephamycin)

Cefotetan, a (7S)-methoxy cephalosporin (cephamycin), is chemically synthesized form 7-MAC [M2129]. The steric hindrance effect that is enhanced by introducing (7S)-methoxy into the β-lactam ring significantly increases the stability of β-lactam antibiotics against β-lactamases, and to some extent reduces the problems of bacterial drug-resistance. Cefotetan has a broad spectrum of activity against Gram-negative and Gram-positive bacteria, and is generally more active against Gram-negative bacteria than the ‘first and second generation’ cephalosporins. Cefotetan is particularly active against Enterobacter but has little activity against Pseudomonas aeruginosa.

References


PubMed Literature


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