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CAS RN: 524955-09-7 | Product Number: C3150

3-Chloro-4-(2-pyridylmethoxy)aniline


Purity: >98.0%(GC)(T)
Synonyms:
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Product Number C3150
Purity / Analysis Method >98.0%(GC)(T)
Molecular Formula / Molecular Weight C__1__2H__1__1ClN__2O = 234.68  
Physical State (20 deg.C) Solid
CAS RN 524955-09-7
Reaxys Registry Number 9908340
PubChem Substance ID 354333976
MDL Number

MFCD08699389

Specifications
Appearance White to Light yellow to Light orange powder to crystal
Purity(GC) min. 98.0 %
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 91.0 to 95.0 °C
Properties (reference)
Melting Point 93 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
Related Laws:
Transport Information:
HS Number 2933.39.9100
Application
A Synthetic Intermediate of Neratinib (NKI-272)

This product is used for the synthesis of neratinib (NKI-272) which is a dual tyrosine kinase inhibitor of the human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases, used as an anticancer agent

References


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