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CAS RN: 85031-59-0 | Product Number: D6147

Dihydroartemisinic acid


Purity: >98.0%(GC)(T)
Synonyms:
  • (R)-2-[(1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]propanoic Acid
  • R,1R,4R,4aS,8aS)-1,2,3,4,4a,5,6,8a-Octahydro-α,4,7-trimethyl-1-naphthaleneacetic Acid
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Product Number D6147
Purity / Analysis Method >98.0%(GC)(T)
Molecular Formula / Molecular Weight C__1__5H__2__4O__2 = 236.36 
Physical State (20 deg.C) Solid
CAS RN 85031-59-0
Reaxys Registry Number 3546237
MDL Number

MFCD16876168

Specifications
Appearance White to Light yellow powder to crystal
Purity(GC) min. 98.0 %
Purity(Neutralization titration) min. 98.0 %
Melting point 137.0 to 141.0 °C
Specific rotation -15.0 to -19.0 deg(C=1, CHCl3)
NMR confirm to structure
Properties (reference)
Melting Point 140 °C
GHS
Related Laws:
Transport Information:
HS Number 2916.20.5000
Application
Dihydroartemisinic Acid: A Biosynthetic Precursor and Synthetic Intermediate of the Antimalarial Agent Artemisinin

Dihydroartemisinic acid is a biosynthetic precursor of the antimalarial agent artemisinin [A2118]. It undergoes a spontaneous endoperoxide-forming cascade reaction to yield artemisinin in the presence of air.1,2) Dihydroartemisinic acid is also a synthetic intermediate of artemisinin from artemisinic acid.3)

References


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