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CAS RN: 1070-11-7 | Product Number: E1011
Ethambutol Dihydrochloride
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Purity: >98.0%(T)
Synonyms:
- (S,S)-N,N'-Bis(1-hydroxy-2-butyl)ethylenediamine Dihydrochloride
- (S,S)-2,2'-(1,2-Ethanediyldiimino)bis-1-butanol Dihydrochloride
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 5G |
$39.00
|
1 | 1 | 22 |
|
| 25G |
$120.00
|
Contact Us | 2 | 35 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | E1011 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__0H__2__4N__2O__2·2HCl = 277.23 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 1070-11-7 |
| Related CAS RN | 74-55-5 |
| PubChem Substance ID | 253662167 |
| Merck Index (14) | 3720 |
| MDL Number | MFCD00216025 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Purity(Argentometric Titration) | min. 98.0 % |
| Melting point | 199.0 to 204.0 °C |
| Specific rotation [a]20/D | +5.0 to +7.0 deg(C=10, H2O) |
Properties (reference)
| Melting Point | 199 °C |
| Specific Rotation | 6° (C=10,H2O) |
| Solubility (slightly sol. in) | Ethanol |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
| RTECS# | EL3854000 |
Transport Information:
| HS Number | 2922.19.9690 |
Application
EMB: A bacteriostatic Antituberculous Agent
(S,S)-N,N'-Bis(1-hydroxy-2-butyl)ethylenediamine dihydrochloride (commonly abbreviated EMB), a chemical synthetic bacteriostatic antituberculous agent, is a strong inhibitor of the mycobacterial cell wall biosynthesis. EMB is usually given in combination with other antituberculous agents, such as isoniazid [I0138], rifampicin [R0079] and pyrazinamide [P0633].
References
- The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol
- The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol
- Biogenesis of the mycobacterial cell wall and the site of action of ethambutol
- Anti-Tuberculosis Drugs
PubMed Literature
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Specifications
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