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CAS RN: 89396-94-1 | Product Number: I0901

Imidapril Hydrochloride


Purity: >98.0%(T)(HPLC)
Synonyms:
  • (4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic Acid Hydrochloride
Documents:
25MG
$126.00
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100MG
$343.00
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Product Number I0901
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__0H__2__7N__3O__6·HCl = 441.91 
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic
Packaging and Container 100MG-Glass Bottle with Plastic Insert (View image)
CAS RN 89396-94-1
Related CAS RN 89371-37-9
Reaxys Registry Number 4835331
PubChem Substance ID 253661853
Merck Index (14) 4911
MDL Number

MFCD00923828

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Specific rotation [a]20/D -65.0 to -69.0 deg(C=1, MeOH)
Properties (reference)
Melting Point 206 °C(dec.)
Specific Rotation -67° (C=1,MeOH)
Solubility in water Soluble
Solubility (slightly sol. in) Ethanol
Solubility (insoluble in) Ether
GHS
Pictogram Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
P405 : Store locked up.
Related Laws:
RTECS# NI8927400
Transport Information:
HS Number 2933.29.4300
Application
Imidapril Hydrochloride: A Non-Sulfhydryl Group and Long-Acting ACE Inhibitor

Imidapril hydrochloride is an ethyl ester prodrug of the active metabolite imidaprilat. Imidapril is a long-acting and non-sulfhydryl group drug with fewer side effects angiotensin-converting enzyme (ACE) inhibitor to suppress the conversion of angiotensin I to angiotensin II and thereby reduce total peripheral resistance (TRP) and systemic blood pressure (BP). (The product is for research purpose only.)

References


PubMed Literature


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