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CAS RN: 1180-71-8 | Product Number: L0258
Limonin
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Purity: >95.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 100MG |
$48.00
|
1 | Contact Us | 5 |
|
| 1G |
$281.00
|
Contact Us | Contact Us | 25 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | L0258 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__6H__3__0O__8 = 470.52 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1180-71-8 |
| Reaxys Registry Number | 1695716 |
| PubChem Substance ID | 253661951 |
| Merck Index (14) | 5494 |
| MDL Number | MFCD00075922 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 95.0 area% |
| Specific rotation [a]20/D | -116 to -120 deg(C=1, Acetone) |
Properties (reference)
| Melting Point | 298 °C |
| Specific Rotation | -117° (C=1,Acetone) |
| Maximum Absorption Wavelength | 285 nm |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Tetrahydrofuran, Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
| RTECS# | RR1122000 |
Transport Information:
| HS Number | 2932.20.4500 |
Application
Limonin: A Chemically-Induced Carcinogenesis Inhibitor and a HIV-1 Replication Inhibitor
Limonin is a non-volatile triterpeneis which is one of two major bitter principles in citrus juice, especially in grapefruit juice. Limonin has been found to inhibit chemical induced carcinogenesis. Limonin is an inducer of glutathione S-transferase, a major detoxifying enzyme system. Additionally, limonin has been reported to inhibit in vitro HIV-1 protease activity.
References
- Limonin and limonoids. Chemistry, biochemistry, and juice bitterness (a review)
- Limonin and nomilin inhibitory effects on chemical-induced tumorigenesis (a review)
- Inhibition of azoxymethane-induced colon carcinogenesis in male F344 rats by the citrus limonoids obacunone and limonin
- Antioxidant Activity of Citrus Limonoids, Flavonoids, and Coumarins
- Suppression of colon carcinogenesis by bioactive compounds in grapefruit
- Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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