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CAS RN: 82034-46-6 | Product Number: L0327

Loteprednol Etabonate


Purity: >98.0%(HPLC)
Synonyms:
  • HGP 1
  • P 5604
  • CDDD 5604
  • Chloromethyl (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylate
  • (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylic Acid Chloromethyl Ester
Documents:
50MG
$112.00
1   Contact Us 17  
250MG
$385.00
6   Contact Us 28  

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Product Number L0327
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__4H__3__1ClO__7 = 466.96 
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 82034-46-6
Reaxys Registry Number 5461012
PubChem Substance ID 468592150
MDL Number

MFCD00870765

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Specific rotation [a]20/D +38.0 to +42.0 deg(C=1, dioxane)
Properties (reference)
Melting Point 225 °C(dec.)
Specific Rotation 40° (C=1,Dioxane)
Maximum Absorption Wavelength 244 nm
Solubility in water Insoluble
Degree of solubility in water 0.0005 g/l   25 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
H413 : May cause long lasting harmful effects to aquatic life.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
Transport Information:
HS Number 2937.22.0000
Application
Loteprednol Etabonate: A “Soft” Corticosteroid

Loteprednol etabonate is a classed as a “soft” corticosteroid designed based on the “inactive metabolite approach”. It is locally metabolized by hydrolysis to the corresponding inactive cortienic acid derivative, and thus limiting or eliminating the associated systemic and local side effects. Corticosteroids play a role in cellular signaling, immune function, inflammation and protein regulation, and they are commonly used to control inflammation. However, there is no generally accepted explanation for the mechanism of action of corticosteroids. Loteprednol etabonate is used to treat inflammations of the eye in clinical. (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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