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CAS RN: 14417-88-0 | Product Number: M3871
Melinamide
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Purity: >95.0%(GC)
Synonyms:
- (9Z,12Z)-N-(1-Phenylethyl)-9,12-octadecadienamide
- AC 223
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 20MG |
$102.00
|
Contact Us | Contact Us | 1 |
|
| 50MG |
$200.00
|
Contact Us | Contact Us | 1 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Supplemental Product Information:
Due to the limited filling volume, some of the product may stick to the inner walls of the bottle.
| Product Number | M3871 |
Purity / Analysis Method 
|
>95.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__6H__4__1NO = 383.62 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 14417-88-0 |
| Reaxys Registry Number | 2950179 |
| MDL Number | MFCD01716255 |
Specifications
| Appearance | Colorless to Light yellow clear liquid |
| Purity(GC) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 217 °C/0.05 mmHg |
GHS
Related Laws:
| RTECS# | OI9410000 |
Transport Information:
| HS Number | 2924.29.7790 |
Application
Melinamide: A Potent and Selective Inhibitor of ACAT
Melinamide is a potent and selective inhibitor of Acyl-Coenzyme A (ACAT, also known as sterol O-acyltransferase or SOAT), which is an intracellular enzyme that catalyzes the formation of cholesteryl esters from cholesterol and fatty acyl-CoA.1,2) Recently, many studies have suggested that ACAT-1 (SOAT-1) plays a critical role in cancer initiation and progression and is an attractive target for novel anticancer therapies.2,3) (The product is for research use only.)
References
- 1) Formation of fatty acid ethyl esters in rat liver microsomes
- 2) Targeting Sterol O-Acyltransferase/Acyl-CoA: Cholesterol Acyltransferase (ACAT): A Perspective on Small-Molecule Inhibitors and Their Therapeutic Potential (a review)
- 3) Cholesterol metabolism: New functions and therapeutic approaches in cancer (a review)
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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