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CAS RN: 10236-47-2 | Product Number: N0073
Naringin
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Purity: >95.0%(T)
Synonyms:
- Naringenin 7-Rhamnoglucoside
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25G |
$37.00
|
2 | 1 | ≥40 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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Supplemental Product Information:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| Product Number | N0073 |
| Purity / Analysis Method | >95.0%(T) |
| Molecular Formula / Molecular Weight | C__2__7H__3__2O__1__4 = 580.54 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 10236-47-2 |
| Related CAS RN | 132203-74-8 |
| Reaxys Registry Number | 102012 |
| PubChem Substance ID | 87573467 |
| MDL Number | MFCD00149445 |
Specifications
| Appearance | White to Yellow to Orange powder to crystal |
| Purity(Neutralization titration) | min. 95.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | -75.0 to -92.0 deg(C=2, EtOH) |
| Water | 4.0 to 9.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 166 °C |
| Specific Rotation | -84° (C=2,EtOH) |
| Degree of solubility in water | 1.1 g/l 25 °C |
| Solubility (soluble in) | Acetone, Alcohol |
GHS
Related Laws:
| RTECS# | QN6340000 |
Transport Information:
| HS Number | 2923.10.0000 |
Application
Bone research
References
- Naringin abrogates osteoclastogenesis and bone resorption via the inhibition of RANKL-induced NF-κB and ERK activation
- Naringin improves bone properties in ovariectomized mice and exerts oestrogen-like activities in rat osteoblast-like (UMR-106) cells
- Effect of Naringin on Bone Cells
Application
Quorum sensing research / Biofilm research
References
- Inhibition of Quorum Sensing (QS) in Yersinia enterocolitica by an Orange Extract Rich in Glycosylated Flavanones
- Suppression of bacterial cell–cell signalling, biofilm formation and type III secretion system by citrus flavonoids
Application
Naringin: A Flavanone Glycoside with Numerous Biological Properties such as Antioxidant and Anti-Inflammatory Activities
Naringin, a major flavanone glycoside, is found in the Chinese herbal medicines, tomatoes, grapefruits, and many other citrus fruits, and is a glycoside form of naringenin [N0072]. It has been demonstrated to possess numerous biological properties such as antioxidant and anti-inflammatory activities. Naringin and naringenin inhibit some drug-metabolizing cytochrome P450 (CYP) 3A4 activity in human liver microsomes, which may result in drug-drug interactions. (The product is for research purpose only.)
References
- Effect of citrus flavonoids, Naringin and Naringenin, on metabolic syndrome and their mechanisms of action (a review)
- Preclinical Evidence for the Pharmacological Actions of Naringin: A Review
Application
Anti-inflammatory Activity of Naringin Acyl Esters by Suppressing Nuclear Factor κB in Macrophages
References
PubMed Literature
Articles/Brochures
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
C of A & Other Certificates
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Analytical Charts
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