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CAS RN: 25137-00-2 | Product Number: N0654

(R)-(-)-3-Piperidinecarboxylic Acid


Purity: >98.0%(T)
Synonyms:
  • (R)-(-)-Nipecotic Acid
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Product Number N0654
Purity / Analysis Method >98.0%(T)
Molecular Formula / Molecular Weight C__6H__1__1NO__2 = 129.16  
Physical State (20 deg.C) Solid
CAS RN 25137-00-2
Reaxys Registry Number 81097
PubChem Substance ID 87573966
MDL Number

MFCD01630787

Specifications
Appearance White powder to crystal
Optical purity(LC) min. 98.0 ee%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D -5.0 to -6.0 deg(C=5, H2O)
Solubility in Water almost transparency
Properties (reference)
Specific Rotation -5.5° (C=5,H2O)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
Related Laws:
Transport Information:
HS Number 2933.39.9100
Application
GABA再取り込み阻害剤ニペコチン酸の活性エナンチオマー,(R)-(-)-ニペコチン酸

(R)-(-)-Nipecotic Acid is aγ-aminobutyric acid (GABA) reuptake inhibitor in vitro, used in scientific research. Some (R)-(-)-nipecotic acid prodrugs have been synthesized and evaluated for their bioactivity in vivo, such as the ethyl ester [N0655]. It is reported that (R)-(-)-nipecotic acid is the active enantiomer of nipecotic acid [N0420].

References


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