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CAS RN: 527-73-1 | Product Number: N0891

2-Nitroimidazole


Purity: >98.0%(T)(HPLC)
Synonyms:
  • Azomycin
Documents:
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Product Number N0891
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__3H__3N__3O__2 = 113.08 
Physical State (20 deg.C) Solid
CAS RN 527-73-1
Reaxys Registry Number 116444
PubChem Substance ID 160871493
Merck Index (14) 921
MDL Number

MFCD00005185

Specifications
Appearance White to Yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 288 °C(dec.)
Solubility (soluble in) Acetone, Methanol, Ethanol
Solubility (insoluble in) Ether, Chloroform
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# NI7875000
Transport Information:
UN Number (DOT-AIR) UN2811
Class (DOT-AIR) 6.1
Packing Group (TCI-A) III
HS Number 2933.29.9000
Application
抗菌活性を有するニトロイミダゾール系抗生物質,2-ニトロイミダゾール

2-Nitroimidazole (azomycin) is a nitroimidazole antibiotic such as metronidazole [M0924] and dimetridazole [D1564]. Azomycin was originally isolated from an unidentified soil bacterium Streptomyces sp. by Maeda et al. Azomycin can now be made by chemical synthesis. Azomycin is active against Gram-positive bacteria including mycobacteria, Gram-negative bacteria and protozoa. Azomycin have been reported as an inhibitor of bacterial ribonucleotide reductase. Meanwhile, several 2-nitroimidazoles have been reported as bioreductive markers for tumour hypoxia.

References


PubMed Literature


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