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CAS RN: 36322-90-4 | Product Number: P1905

Piroxicam


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 4-Hydroxy-2-methyl-3-(2-pyridylcarbamoyl)-2H-1,2-benzothiazine 1,1-Dioxide
  • 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide
Documents:
10G
$225.00
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Product Number P1905
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__5H__1__3N__3O__4S = 331.35 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 36322-90-4
Reaxys Registry Number 627692
PubChem Substance ID 125307705
Merck Index (14) 7506
MDL Number

MFCD00057317

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 199.0 to 203.0 °C
NMR confirm to structure
Properties (reference)
Melting Point 201 °C
Maximum Absorption Wavelength 358(H2O) nm
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# DL0705000
Transport Information:
UN Number (DOT-AIR) UN2811
Class (DOT-AIR) 6.1
Packing Group (TCI-A) III
HS Number 2935.90.9500
Application
Piroxicam: A Nonsteroidal Anti-Inflammatory Drug (NSAID) with Antitumor Activity

Piroxicam is a nonsteroidal and non-selective cyclooxygenase (COX) inhibitor which has anti-inflammatory effects. The mechanism of action is mainly by inhibition of the enzyme COX in the arachidonic acid metabolism pathway, resulting in reduced prostaglandin synthesis. In addition, the mechanisms are not completely defined but piroxicam has been reported its antiangiogenic effects and induction of apoptosis in cancer cells, as well as other NSAIDs. (The product is for research purpose only.)

References


PubMed Literature


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