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CAS RN: 84-02-6 | Product Number: P2368

Prochlorperazine Dimaleate


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine Dimaleate
Product Documents:
5G
$52.00
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Product Number P2368
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__0H__2__4ClN__3S·2C__4H__4O__4 = 606.09 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Condition to Avoid Light Sensitive
CAS RN 84-02-6
Related CAS RN 58-38-8
Reaxys Registry Number 3861788
PubChem Substance ID 354335064
Merck Index (14) 7761
MDL Number

MFCD00069330

Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Melting Point 194 °C(dec.)
Maximum Absorption Wavelength 313 nm (MeOH)
Solubility in water Insoluble
Solubility (insoluble in) Diethyl ether, Ethanol
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H360 : May damage fertility or the unborn child.
H350 : May cause cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# SO3150000
Transport Information:
HS Number 2934.99.3000
Application
Prochlorperazine Dimaleate: A Dopamine Receptor Antagonist with Antipsychotic Activity

Prochlorperazine dimaleate is a phenothiazine antipsychotic agent with a piperazine moiety in the side chain. Prochlorperazine possesses strong antiemetic and antipsychotic activity with less sedative action than chlorpromazine [C2481]. The precise mechanism of actions is not fully understood. However, prochlorperazine works as a dopamine and α-adrenergic receptors antagonist, and the functions may be related to the therapeutic effect in psychotic conditions. In addition, there is good evidence to suggest that, in common with other phenothiazine agents, prochlorperazine has antibacterial activity. (The product is for research purpose only.)

References


PubMed Literature


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