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CAS RN: 124436-59-5 | Product Number: P2665
Pirodavir
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Purity: >95.0%(HPLC)
Synonyms:
- Ethyl 4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoate
- 4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoic Acid Ethyl Ester
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10MG |
$154.00
|
Contact Us | Contact Us | 18 |
|
| 50MG |
$536.00
|
Contact Us | Contact Us | 19 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | P2665 |
Purity / Analysis Method 
|
>95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__7N__3O__3 = 369.47 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 124436-59-5 |
| Reaxys Registry Number | 8162239 |
| PubChem Substance ID | 468592664 |
| MDL Number | MFCD00866965 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Elemental analysis(Nitrogen) | 10.50 to 12.30 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 125 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2933.99.7500 |
Application
Pirodavir: A Broad-Spectrum Anti-Picornavirus Agent
Pirodavir (R77975) is a broad-spectrum anti-picornavirus agent, and is active against both group A and group B rhinovirus serotypes.1) Picornaviridae represent a very large family of small RNA viruses. Rhinoviruses belong to the genus Enterovirus in the family Picornaviridae, and is a kind of with highly infectious which is responsible for many of the severe exacerbations of asthma and chronic obstructive pulmonary disease (COPD). However, a clinical trial report demonstrated that intranasal sprays of pirodavir were associated with no clinical benefit in treating naturally occurring rhinovirus colds.2) (The product is for research purpose only.)
References
- 1) In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviral activity
- 2) ntranasal pirodavir (R77975) treatment of rhinovirus colds
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