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CAS RN: 117976-90-6 | Product Number: R0115

Rabeprazole Sodium Salt


Purity: >98.0%(HPLC)
Synonyms:
Documents:
100MG
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Product Number R0115
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__8H__2__0N__3NaO__3S = 381.43 
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic,Heat Sensitive
Packaging and Container 100MG-Glass Bottle with Plastic Insert (View image)
CAS RN 117976-90-6
Related CAS RN 117976-89-3
Reaxys Registry Number 7561607
PubChem Substance ID 253660182
Merck Index (14) 8089
MDL Number

MFCD02092688

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 95.0 %
Properties (reference)
Melting Point 150 °C
Solubility (soluble in) Methanol
Solubility (insoluble in) Ether
GHS
Related Laws:
Transport Information:
HS Number 2933.99.9701
Application
A More Potent Proton Pump Inhibitor, Rabeprazole Sodium

Rabeprazole sodium is a new substituted benzimidazole proton pump inhibitor with several differences compared with existing proton pump inhibitors. Rabeprazole sodium is a more potent inhibitor of H+,K+-ATPase (hydrogen-potassium adenosine triphosphatase) and acid secretion than omeprazole [O0359], and is a more rapid inhibitor of proton pumps than omeprazole, lansoprazole [L0233], or pantoprazole sulfide [P2066]. Furthermore, in vitro studies have shown that rabeprazole sodium possesses more potent antibacterial properties against the growth of H. pylori than other proton pump inhibitors.

References


PubMed Literature


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