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CAS RN: 52-01-7 | Product Number: S0260

Spironolactone


Purity: >98.0%(HPLC)
Synonyms:
Documents:
1G
$31.00
1   1   27  
5G
$85.00
4   1   2  

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Product Number S0260
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__4H__3__2O__4S = 416.58 
Physical State (20 deg.C) Solid
CAS RN 52-01-7
Reaxys Registry Number 57767
PubChem Substance ID 87575785
SDBS (AIST Spectral DB) 11014
Merck Index (14) 8760
MDL Number

MFCD00082250

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(UV-vis method) min. 95.0 %
Specific rotation [a]20/D -34.0 to -38.0 deg(C=1, CHCl3)
Solubility in EtOH very faint turbidity
Properties (reference)
Specific Rotation -36° (C=1,CHCl3)
GHS
Related Laws:
RTECS# TU4725000
Transport Information:
HS Number 2932.20.5050
Application
Spironolactone: An Aldosterone Receptor Antagonist

Spironolactone is an aldosterone (a mineralocorticoid) receptor antagonist. Spironolactone binds to the receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule, and causes increased amounts of sodium and water to be excreted, while potassium is retained. By this mechanisms of action, spironolactone acts both as a diuretic and as an antihypertensive agent. (The product is for research purpose only.)

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