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CAS RN: 53885-35-1 | Product Number: T3110
Ticlopidine Hydrochloride
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine Hydrochloride
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 5G |
$61.00
|
1 | 1 | 33 |
|
| 25G |
$159.00
|
Contact Us | Contact Us | 4 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | T3110 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__4H__1__4ClNS·HCl = 300.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 53885-35-1 |
| Related CAS RN
|
55142-85-3 |
| Reaxys Registry Number | 4037097 |
| PubChem Substance ID | 253661993 |
| Merck Index (14) | 9421 |
| MDL Number | MFCD00079606 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 208.0 to 212.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 210 °C |
| Maximum Absorption Wavelength | 295 nm (H__2O) |
| Solubility in water | Soluble |
| Solubility (soluble in) | Methanol |
| Solubility (slightly sol. in) | Ethanol |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | XJ9089100 |
Transport Information:
| HS Number | 2934.99.3000 |
Application
Ticlopidine Hydrochloride: A Thienopyridine Adenosine-5'-Diphosphate (ADP) Receptor Antagonist
Ticlopidine hydrochloride, clopidogrel sulfate [C2556], and prasugrel [P2024] belong to the same family of thienopyridine adenosine-5'-diphosphate (ADP) receptor antagonists. Although ticlopidine was discovered more than 30 years ago, it was only recently that the mechanism of action of ADP-receptor antagonists was characterized in detail. They achieve antiplatelet effects by inhibiting the binding of ADP to its platelet P2Y12 ADP receptor. They are prodrugs and are then converted to thiol-containing active metabolites through a corresponding thiolactone.
References
- The antiplatelet effects of ticlopidine and clopidogrel (a review)
- Ticlopidine and clopidogrel (a review)
- Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine
- Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis (a review)
- Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans
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Specifications
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