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CAS RN: 480-18-2 | Product Number: T3666
(+)-Taxifolin
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Purity: >95.0%(T)(HPLC)
Synonyms:
- (2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone
- (2R,3R)-Dihydroquercetin
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 200MG |
$114.00
|
4 | 2 | ≥100 |
|
| 1G |
$344.00
|
1 | 1 | ≥40 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | T3666 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__2O__7 = 304.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 480-18-2 |
| Reaxys Registry Number | 93548 |
| PubChem Substance ID | 468592883 |
| MDL Number | MFCD00006845 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 95.0 %(calcd.on dried substance) |
| Specific rotation [a]20/D | +19.0 to +23.0 deg(C=1, methanol) |
| Water | max. 10.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 242 °C |
| Maximum Absorption Wavelength | 292 nm (MeOH) |
GHS
Related Laws:
| RTECS# | LK6920000 |
Transport Information:
| HS Number | 2932.99.7000 |
Application
Efflux pump research
(+)-Taxifolin has been reported to inhibit efflux pump thereby decreasing the minimum inhibitory concentrations (MICs) of Isoniazid [I0138] against Mycobacterium.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Modulation of isoniazid susceptibility by flavonoids in Mycobacterium
- The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1
- A DFT study of the reactivity of OH groups in quercetin and taxifolin antioxidants: The specificity of the 3-OH site
- Taxifolin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-oxidative effect and modulation of NF-kappa B activation
- Dihydroquercetin: More than just an impurity? (a review)
- Simultaneous quantification of five major bioactive flavonoids in Rhizome Smilacis Glabrae by high-performance liquid chromatography
Application
Quorum sensing research
Reference
Application
(+)-Taxifolin: A Bioactive Flavonoid with Antioxidant and Antitumor Activities
(+)-Taxifolin (dihydroquercetin) is a bioactive flavonoid found in many plants. It has been reported that (+)-taxifolin has many bioactivities, including antioxidant, antitumor, antiviral, and anti-cardiovascular system disease activities. (The product is for research purpose only.)
References
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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