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CAS RN: 1156-19-0 | Product Number: T4168
Tolazamide
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N-(Azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamide
- N-(1-Azepanylcarbamoyl)-4-methylbenzenesulfonamide
- 1-(Hexahydro-1H-azepin-1-yl)-3-(p-toluenesulfonyl)urea
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 100MG |
$243.00
|
Contact Us | Contact Us | 16 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | T4168 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__2__1N__3O__3S = 311.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 1156-19-0 |
| Reaxys Registry Number | 1323565 |
| MDL Number | MFCD00083504 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 163.0 to 167.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 165 °C |
GHS
Related Laws:
| RTECS# | YT4400000 |
Transport Information:
| HS Number | 2933.99.7900 |
Application
Tolazamide: A Sulfonylurea (SU) Compound
Tolazamide (U-17835) is a sulfonylurea (SU) compound used in the treatment of non-insulin-dependent diabetes mellitus. Tolazamide appears to lower blood glucose acutely by stimulating the release of insulin from the pancreas, an effect that depends on the function of beta cells in the pancreatic islets. (The product is for research purpose only.)
References
- Potentiation of Insulin Action by a Sulfonylurea in Primary Cultures of Hepatocytes from Normal and Diabetic Rats
- Biological activities of sulfonamides (a review)
- Characterization of tolazamide binding with glycated and normal human serum albumin by using high-performance affinity chromatography
- Screening, library-assisted identification and validated quantification of oral antidiabetics of the sulfonylurea-type in plasma by atmospheric pressure chemical ionization liquid chromatography-mass spectrometry
- Detection of anti-diabetics in equine plasma and urine by liquid chromatography-tandem mass spectrometry
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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