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CAS RN: 5536-17-4 | Product Number: V0175

Vidarabine


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 9-β-D-Arabinofuranosyl-9H-purin-6-amine
  • Adenine 9-β-D-Arabinofuranoside
  • 6-Amino-9-β-D-arabinofuranosylpurine
  • Ara-A
Documents:
5G
$85.00
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25G
$255.00
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Product Number V0175
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__0H__1__3N__5O__4 = 267.25 
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Hygroscopic
CAS RN 5536-17-4
Reaxys Registry Number 624881
PubChem Substance ID 468593117
MDL Number

MFCD00065471

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation -2.0 to -4.0 deg(C=1, DMF)
NMR confirm to structure
Properties (reference)
Melting Point 257 °C
Maximum Absorption Wavelength 260(H2O) nm
GHS
Related Laws:
RTECS# AU6200000
Transport Information:
HS Number 2934.99.9001
Application
Vidarabine: An Arabinosyladenine with Ant-Virus and Anti-Cancer Activities

Vidarabine (arabinosyladenine, ara-A) is a synthetic purine nucleoside, and was first synthesized by Lee et al. in 1960. Vidarabine was originally intended as an anti-cancer agent, while the anti-viral activity against herpesvirus and vaccinia virus was reported by Rudder et al in 1965. And also the activity against varicella-zoster virus was reported by Miller et al. in 1968. Vidarabine had a broad-spectrum activity against DNA viruses but little activity against RNA viruses. Vidarabine is converted to the active form vidarabine triphosphate (ara-ATP) which inhibits viral DNA polymerase activity in vitro and in vivo. (The product is for research purpose only.)

References

Documents (Note: Some products will not have analytical charts available.)
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