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CAS RN: 6754-58-1 | Product Number: X0068
Xanthohumol
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Purity: >97.0%(HPLC)(qNMR)
Synonyms:
- (E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)propenone
- 2',4,4'-Trihydroxy-6'-methoxy-3'-prenylchalcone
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|---|
| 25MG |
$814.00
|
Contact Us | Contact Us | 6 |
|
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| Product Number | X0068 |
Purity / Analysis Method 
|
>97.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__1H__2__2O__5 = 354.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| CAS RN | 6754-58-1 |
| Reaxys Registry Number | 2226282 |
| PubChem Substance ID | 253659967 |
| MDL Number | MFCD00210576 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(qNMR) | min. 97.0 % |
| Melting point | 158.0 to 163.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 159 °C |
GHS
Related Laws:
| RTECS# | UD5574117 |
Transport Information:
| HS Number | 2914.50.3000 |
Application
Paraptosis research
Reference
- Xanthohumol induces paraptosis of leukemia cells through p38 mitogen activated protein kinase signaling pathway
- 1)Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
- 2)Pharmacognostic and pharmacological profile of Humulus lupulus L.
- 3)Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines
- 4)Cancer chemopreventive activity of xanthohumol, a natural product derived from hop
- 5)Bone resorption inhibitors from hop extract
- 6)Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro
- 7)Xanthohumols, diacylglycerol acyltransferase inhibitors, from Humulus lupulus
Application
A Bioactive Polyphenol in Hops and Beer
Xanthohumol is the prenylated chalcone isolated from the female inflorescences of the hop plant (Humulus lupulus L.), an ingredient of beer, have long been used in traditional medicine. Xanthohumol is one of the bioactive substances, and has been reported that it has various pharmacological activities, including antioxidant, anti-inflammatory, anti-proliferative, and osteogenic effects. (The product is for research purpose only)
References
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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