Product Document Searching Made Easy by 2D Code! | TCI Chemistry News October 2025 | [TCIPracticalExample] Di-Cbz Guanidinylation of Amine... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 208255-80-5 | Product Number: D4257
DAPT
×
![]()
×
Purity: >97.0%(HPLC)
Synonyms:
- (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu
- (3,5-Difluorophenylacetyl)-L-alanyl-L-2-phenylglycine tert-Butyl Ester
- tert-Butyl (S)-2-[(S)-2-[2-(3,5-Difluorophenyl)acetamido]propanamido]-2-phenylacetate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
$409.00
|
11 | 0 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | D4257 |
Purity / Analysis Method 
|
>97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__6F__2N__2O__4 = 432.47 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 208255-80-5 |
| Reaxys Registry Number | 9588440 |
| PubChem Substance ID | 253659655 |
| MDL Number | MFCD04974585 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Elemental analysis(Nitrogen) | 6.20 to 6.70 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
| H.S.code* | 2924.29-000 |
Application
γ-Secretase Inhibitor
References
- 1)Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain
- 2)The Notch signaling inhibitor DAPT down-regulates cdk5 activity and modulates the distribution of neuronal cytoskeletal proteins
- 3)Notch signaling: A simple pathway becomes complex
- 4)The Notch response inhibitor DAPT enhances neuronal differentiation in embryonic stem cell-derived embryoid bodies independently of sonic hedgehog signaling
PubMed Literature
Product Articles
[TCIMAIL No.162] γ-Secretase Inhibitor[Featured Products] Regenerative Medicine Related Reagents
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.
Other Documents
Related Products
![DAPT [Optimized for Cell Culture]](/medias/Tci-300-D6295.jpg?context=bWFzdGVyfHJvb3R8MTA3ODR8aW1hZ2UvanBlZ3xhR0UxTDJnMFpTODVORFk0TlRRMk56RXhOVGd5TDFSamFTMHpNREJmUkRZeU9UVXVhbkJufDMyNTExODg3MjYzNTFmMjNjYzk3MjBjZjIzOWE1YzAxNWYyYWFlNDExZTZmN2VlZWJiMmFmM2RmYTAxNTBhMDc "DAPT [Optimized for Cell Culture]")
DAPT [Optimized for Cell Culture]
| Product # | D6295 |
| CAS RN | 208255-80-5 |
| Purity / Analysis Method: |